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Hprttm1(CAG-NRIP1)Vcls
Targeted Allele Detail
Nomenclature
Symbol: Hprttm1(CAG-NRIP1)Vcls
Name: hypoxanthine guanine phosphoribosyl transferase; targeted mutation 1, Vincent Cavailles
MGI ID: MGI:5574440
Synonyms: RIPTg
Gene: Hprt  Location: ChrX:52988137-53021659 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211324
Parent Cell Line:  BPES (ES Cell)
Strain of Origin:  (129-Hprtb-m3 x C57BL/6)F1
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Hprttm1(CAG-NRIP1)Vcls expresses 1 gene
 
Mutation detailsA targeting construct inserted into the locus a CAG promoter driving ubiquitous expression of the human NRP1 cDNA. (J:211324)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt Mutation:  30 strains or lines available
References
Original:  J:211324 Lapierre M, et al., RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis. J Clin Invest. 2014 May 1;124(5):1899-913
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory