Myh9^tm9.1Rsad
Targeted Allele Detail

Summary

• Symbol: Myh9^tm9.1Rsad
• Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 9.1, Robert S Adelstein
• MGI ID: MGI:5566899
• Synonyms: Myh9^E1841K
• Gene: Myh9 Location: Chr15:77644787-77726375 bp, - strand Genetic Position: Chr15, 36.81 cM
• Alliance: Myh9^tm9.1Rsad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175367
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: A 1.1-kb DNA fragment containing exon 39 and exon 40 was amplified from BAC clone 144L21 and the E1841K mutation was introduced into exon 39 by PCR. A floxed neomycin selection cassette was inserted upstream of exon 39 but later excised by cre expression. (J:175367)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myh9 Mutation: 219 strains or lines available

References

• Original: J:175367 Zhang Y, et al., Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood. 2012;119(1):238-5
• All: 4 reference(s)