Pax7^tm1.1Thbr
Targeted Allele Detail

Summary

• Symbol: Pax7^tm1.1Thbr
• Name: paired box 7; targeted mutation 1.1, Thomas Braun
• MGI ID: MGI:5548068
• Synonyms: Pax7^loxP-Gu
• Gene: Pax7 Location: Chr4:139464373-139560839 bp, - strand Genetic Position: Chr4, 70.83 cM
• Alliance: Pax7^tm1.1Thbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202693
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the 5'UTR. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. (J:202693)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax7 Mutation: 39 strains or lines available

References

• Original: J:202693 Gunther S, et al., Myf5-positive satellite cells contribute to pax7-dependent long-term maintenance of adult muscle stem cells. Cell Stem Cell. 2013 Nov 7;13(5):590-601
• All: 1 reference(s)