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Pon3tm1Lus
Targeted Allele Detail
Nomenclature
Symbol: Pon3tm1Lus
Name: paraoxonase 3; targeted mutation 1, Aldons J Lusis
MGI ID: MGI:5544271
Gene: Pon3  Location: Chr6:5220852-5256286 bp, - strand  Genetic Position: Chr6, 1.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:204799
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation detailsNo details provided. Western blot analysis confirmed the absence of protein expression in liver mitochondria. (J:204799)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pon3 Mutation:  3 strains or lines available
References
Original:  J:204799 Schweikert EM, et al., PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death. Cell Death Differ. 2012 Sep;19(9):1549-60
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory