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Pgap3tm1.1Ymra
Targeted Allele Detail
Summary
Symbol: Pgap3tm1.1Ymra
Name: post-GPI attachment to proteins 3; targeted mutation 1.1, Yoshiko Murakami
MGI ID: MGI:5538630
Gene: Pgap3  Location: Chr11:98279503-98291316 bp, - strand  Genetic Position: Chr11, 61.75 cM
Alliance: Pgap3tm1.1Ymra page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181221
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 7. A neomycin resistance cassette with a 3' loxP site was inserted downstream of the coding sequence in the 3' UTR in exon 8. Cre-mediated recombination removed the coding sequence of exon 7 and 8. (J:181221)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pgap3 Mutation:  29 strains or lines available
References
Original:  J:181221 Murakami H, et al., Enhanced response of T lymphocytes from Pgap3 knockout mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins. Biochem Biophys Res Commun. 2012 Jan 27;417(4):1235-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory