Ube2mtm1.1(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Ube2mtm1.1(KOMP)Wtsi |
Name: |
ubiquitin-conjugating enzyme E2M; targeted mutation 1.1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5515621 |
Gene: |
Ube2m Location: Chr7:12769047-12772202 bp, - strand Genetic Position: Chr7, 7.73 cM
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Alliance: |
Ube2mtm1.1(KOMP)Wtsi page
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IMPC: |
Ube2m gene page |
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Mutant Cell Line: |
EPD0391_5_A05 |
Germline Transmission: |
Earliest citation of germline transmission:
J:188991
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 891 starting at position 12769752 and ending at position 12770643 of Chromosome 7 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site was followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site, and Cre-mediated excision deleted this neomycin selection cassette.
(J:148605, J:173534, J:188991)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
7 reference(s) |
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