Plekhh1tm1e(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Plekhh1tm1e(EUCOMM)Hmgu |
Name: |
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5514540 |
Gene: |
Plekhh1 Location: Chr12:79075937-79128429 bp, + strand Genetic Position: Chr12, 35.51 cM
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IMPC: |
Plekhh1 gene page |
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Mutant Cell Lines: |
HEPD0907_5_D08, HEPD0907_5_D10, HEPD0907_5_G08, HEPD0907_5_H08, HEPD0907_5_H09, HEPD0907_5_H12 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8.N4 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_GT0_LF2A_LacZ_BetactP_neo
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Mutation details: The L1L2_GT0_LF2A_LacZ_BetactP_neo cassette was inserted at position 79108381 of Chromosome 12 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
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Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
1 reference(s) |
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