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Targeted Allele Detail
Symbol: Uba6tm1Whpr
Name: ubiquitin-like modifier activating enzyme 6; targeted mutation 1, Wade Harper
MGI ID: MGI:5509054
Synonyms: Uba6flox
Gene: Uba6  Location: Chr5:86258579-86320602 bp, - strand  Genetic Position: Chr5, 43.56 cM
Germline Transmission:  Earliest citation of germline transmission: J:198126
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA targeting vector was designed to insert a loxP site upstream of exon 16. A second loxP site, followed by a FRT-flanked neomycin resistance (neo) cassette, was inserted downstream of exon 17. (J:198126)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Uba6 Mutation:  36 strains or lines available
Original:  J:198126 Lee PC, et al., Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system. Mol Cell. 2013 Apr 25;50(2):172-84
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory