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Targeted Allele Detail
Symbol: Ctbp2tm1Sud
Name: C-terminal binding protein 2; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:5503960
Synonyms: Ctbp2REG, RBEKI+neo
Gene: Ctbp2  Location: Chr7:132589292-132726083 bp, - strand  Genetic Position: Chr7, 76.32 cM
Germline Transmission:  Earliest citation of germline transmission: J:233453
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac x C57BL/6J
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Modified isoform(s))
Mutation:    Insertion
Mutation detailsThe endogenous N-terminal Ribeye A-domain was replaced with a loxP site followed by the Ribeye A domain cDNA fused to GCaMP3 (a GFP based calcium sensor). The coding region is followed by a polyA signal, an FRT-flanked PGK-neomycin selection cassette, and a 3' prime loxP site. This knock-in allele expresses a tagged C-terminally truncated Ribeye isoform without the B-domain. (J:233453)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ctbp2 Mutation:  558 strains or lines available
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
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