Ctbp2^tm1Sud
Targeted Allele Detail

Summary

• Symbol: Ctbp2^tm1Sud
• Name: C-terminal binding protein 2; targeted mutation 1, Thomas C Sudhof
• MGI ID: MGI:5503960
• Synonyms: Ctbp2^REG, RBE^KI+neo
• Gene: Ctbp2 Location: Chr7:132589292-132726083 bp, - strand Genetic Position: Chr7, 76.32 cM
• Alliance: Ctbp2^tm1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233453
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac x C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Modified isoform(s))
• Mutation: Insertion
• Mutation details: The endogenous N-terminal Ribeye A-domain was replaced with a loxP site followed by the Ribeye A domain cDNA fused to GCaMP3 (a GFP based calcium sensor). The coding region is followed by a polyA signal, an FRT-flanked PGK-neomycin selection cassette, and a 3' prime loxP site. This knock-in allele expresses a tagged C-terminally truncated Ribeye isoform without the B-domain. (J:233453)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ctbp2 Mutation: 572 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 4 reference(s)