Tslp^tm1Sfz
Targeted Allele Detail

Summary

• Symbol: Tslp^tm1Sfz
• Name: thymic stromal lymphopoietin; targeted mutation 1, Steven Ziegler
• MGI ID: MGI:5503051
• Gene: Tslp Location: Chr18:32948436-32952850 bp, + strand Genetic Position: Chr18, 18.12 cM
• Alliance: Tslp^tm1Sfz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199558
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 2 through 5. (J:199558)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tslp Mutation: 14 strains or lines available

References

• Original: J:199558 Han H, et al., Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma. Mucosal Immunol. 2012 May;5(3):342-51
• All: 4 reference(s)