Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tslptm1Sfz targeted mutation 1, Steven Ziegler MGI:5503051 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice sensitized in the skin with TSLP and ovalbumin and challenged intranasally with ovalbumin exhibit a robust response as in control mice
|
| N |
• mice sensitized in the skin with TSLP and ovalbumin and challenged intranasally with ovalbumin exhibit a robust response as in control mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice exposed to ovalbumin and restimulated exhibit early impairment in Th2 response (IL5 and IL13 cytokine production) compared with control mice
• however, mice exhibit normal later stages of allergen-induced responses and allergic airway response or Th2 immunity
|
|
• mice exposed to ovalbumin and restimulated exhibit impaired Th2 cytokine (IL5 and IL13) production compared with control mice
• however, previously skewed T cell population exhibit normal Th2 cytokine productions
|
|
• from ovalbumin restimulated lung draining lymph nodes
|
|
• from ovalbumin restimulated lung draining lymph nodes
|
|
• mice exposed to ovalbumin and restimulated exhibit early impairment in Th2 response (IL5 and IL13 cytokine production) compared with control mice
• however, mice exhibit normal later stages of allergen-induced responses and allergic airway response or Th2 immunity
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 09/30/2025 MGI 6.24 |
|
|
|
||
