Ptf1a/Ptf1aos^tm4Kymm
Targeted Allele Detail

Summary

• Symbol: Ptf1a/Ptf1aos^tm4Kymm
• Name: pancreas specific transcription factor 1a, opposite strand; targeted mutation 4, Ken-ichi Yamamura
• MGI ID: MGI:5503025
• Synonyms: Gm13336-Ptf1a^lacZ
• Gene: Ptf1aos Location: Chr2:19446319-19451485 bp, - strand Genetic Position: Chr2, 13.36 cM
• Alliance: Ptf1a/Ptf1aos^tm4Kymm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195133
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Recombination of Ptf1a/Ptf1aos^tm1Kymm exchanged the floxed neomycin resistance cassette with with a lacZ gene, FRT site, puromycin resistance cassette and lox2272 site. This allele was generated in ES cells containing Etn2^Sd. (J:195133)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptf1aos Mutation: 1 strain or line available

References

• Original: J:195133 Semba K, et al., Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013 Feb;9(2):e1003204
• All: 1 reference(s)