Rab38^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rab38^m1Btlr
• Name: RAB38, member RAS oncogene family; mutation 1, Bruce Beutler
• MGI ID: MGI:5497994
• Synonyms: fenrir
• Gene: Rab38 Location: Chr7:88079481-88140780 bp, + strand Genetic Position: Chr7, 49.19 cM
• Alliance: Rab38^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Capillary sequencing of the mutated genes identified the causative mutation as a T to A transversion at base pair 88450541 (v38) on Chromosome 7 in the GenBank genomic region NC_000073 encoding Rab38. The mutation corresponds to residue 263 in the mRNA sequence within exon 2 of 3 total exons. The mutation results in a Isoleucine (I) to Asparagine (N) at position 88 (I88N). (J:198554)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rab38 Mutation: 15 strains or lines available

Notes

Whole genome HiSeq sequencing of the G1 grandsire identified 61 mutations.

References

• Original: J:198554 Beutler B, Direct data submission for a Rab38 allele. MGI Direct Data Submission. 2013
• All: 1 reference(s)