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Adgrf5tm1.2Bstc
Targeted Allele Detail
Nomenclature
Symbol: Adgrf5tm1.2Bstc
Name: adhesion G protein-coupled receptor F5; targeted mutation 1.2, Brad St Croix
MGI ID: MGI:5490511
Gene: Adgrf5  Location: Chr17:43360451-43459557 bp, + strand  Genetic Position: Chr17, 19.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:196943
Parent Cell Line:  v6.4 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to insert a loxP site upstream of exon 2 and a frt- and loxP-flanked neomycin resistance (neo) cassette downstream of exon 2. Cre-mediated recombination removed the neo cassette and exon 2. (J:196943)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgrf5 Mutation:  44 strains or lines available
References
Original:  J:196943 Yang MY, et al., Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116. Cell Rep. 2013 May 30;3(5):1457-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory