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Targeted Allele Detail
Symbol: Myh9tm1.2Gac
Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 1.2, Christian Gachet
MGI ID: MGI:5489745
Gene: Myh9  Location: Chr15:77760587-77842175 bp, - strand  Genetic Position: Chr15, 36.81 cM
Germline Transmission:  Earliest citation of germline transmission: J:195436
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 1, and a floxed neo cassette was inserted downstream of exon 1. Cre-mediated recombination removed the neo cassette and exon 1. (J:195436)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myh9 Mutation:  187 strains or lines available
Original:  J:195436 Schachtner H, et al., Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane. Blood. 2013 Mar 28;121(13):2542-52
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory