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Il12rb2tm1.1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Il12rb2tm1.1(KOMP)Vlcg
Name: interleukin 12 receptor, beta 2; targeted mutation 1.1, Velocigene
MGI ID: MGI:5488781
Gene: Il12rb2  Location: Chr6:67291318-67376188 bp, - strand  Genetic Position: Chr6, 30.81 cM
Mutation
origin
Mutant Cell Line:  15411B-D1
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 10705bp between positions 67301237-67311941 of Chromosome 6 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)
Expression
In Mice Carrying this Mutation: 6 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il12rb2 Mutation:  4 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/07/2020
MGI 6.15
The Jackson Laboratory