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Targeted Allele Detail
Symbol: Chst10tm1Mifu
Name: carbohydrate sulfotransferase 10; targeted mutation 1, Minoru Fukuda
MGI ID: MGI:5485156
Gene: Chst10  Location: Chr1:38902948-38937242 bp, - strand  Genetic Position: Chr1, 17.24 cM
Enlarged uteri in Chst10tm1Mifu/Chst10tm1Mifu mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:195651
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neo cassette replaced the coding sequence in exon 5. Immunohistochemistry confirmed the absence of protein expression in the hippocampus. (J:195651)
Generation of the Chst10tm1Mifu allele
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Chst10 Mutation:  13 strains or lines available
Original:  J:195651 Suzuki-Anekoji M, et al., In vivo regulation of steroid hormones by the Chst10 sulfotransferase in mouse. J Biol Chem. 2013 Feb 15;288(7):5007-16
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory