Zic3^tm1.1Smwa
Targeted Allele Detail

Summary

• Symbol: Zic3^tm1.1Smwa
• Name: zinc finger protein of the cerebellum 3; targeted mutation 1.1, Stephanie M Ware
• MGI ID: MGI:5476827
• Synonyms: Zic3^flox
• Gene: Zic3 Location: ChrX:57075988-57081990 bp, + strand Genetic Position: ChrX, 32.56 cM
• Alliance: Zic3^tm1.1Smwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194989
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a FRT and loxP flanked neo cassette was inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:194989)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zic3 Mutation: 37 strains or lines available

References

• Original: J:194989 Sutherland MJ, et al., Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning. Hum Mol Genet. 2013 May 15;22(10):1913-23
• All: 1 reference(s)