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Targeted Allele Detail
Symbol: Sp2tm1.1Htg
Name: Sp2 transcription factor; targeted mutation 1.1, H Troy Ghashghaei
MGI ID: MGI:5471237
Synonyms: Sp2F
Gene: Sp2  Location: Chr11:96953332-96982129 bp, - strand  Genetic Position: Chr11, 60.17 cM, cytoband D
Germline Transmission:  Earliest citation of germline transmission: J:194076
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 3 and 4 floxed. (J:194076)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sp2 Mutation:  146 strains or lines available
Original:  J:194076 Liang H, et al., Neural development is dependent on the function of specificity protein 2 in cell cycle progression. Development. 2013 Feb 1;140(3):552-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory