Uba6tm1.1Whpr
Targeted Allele Detail
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Symbol: |
Uba6tm1.1Whpr |
Name: |
ubiquitin-like modifier activating enzyme 6; targeted mutation 1.1, Wade Harper |
MGI ID: |
MGI:5470301 |
Synonyms: |
Uba6flox |
Gene: |
Uba6 Location: Chr5:86258579-86320602 bp, - strand Genetic Position: Chr5, 43.56 cM
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Alliance: |
Uba6tm1.1Whpr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:198126
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Parent Cell Line: |
iTL BA1 (ES Cell)
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Strain of Origin: |
(C57BL/6NTac x 129S6/SvEvTac)F1
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 16. A second loxP site, followed by a frt-flanked neomycin resistance (neo) cassette, was inserted downstream of exon 17. Flp-mediated recombination removed the neo cassette and left exons 16 and 17 floxed.
(J:198126)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Uba6 Mutation: |
59 strains or lines available
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Original: |
J:198126 Lee PC, et al., Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system. Mol Cell. 2013 Apr 25;50(2):172-84 |
All: |
1 reference(s) |
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