Arid1a^m1Mag
Chemically induced Allele Detail

Summary

• Symbol: Arid1a^m1Mag
• Name: AT-rich interaction domain 1A; mutation 1, Terry Magnuson
• MGI ID: MGI:5469314
• Synonyms: Arid1a^V1068G
• Gene: Arid1a Location: Chr4:133406319-133484080 bp, - strand Genetic Position: Chr4, 66.25 cM
• Alliance: Arid1a^m1Mag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192829
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: ENU-mutagenesis induced a T-to-G mutation (T is base 3203 in NCBI Reference Sequence NM_001080819.1) that results in the amino acid substitution of glycine for valine at position 1068 (V1068G). This allele is hypomorphic. (J:192829)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Arid1a Mutation: 179 strains or lines available

Notes

Either E14 (129P2/OlaHsd) or CT129 (129S/Sv) ES cells

References

• Original: J:192829 Chandler RL, et al., ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF. Mol Cell Biol. 2013 Jan;33(2):265-80
• All: 2 reference(s)