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Ccdc88atm4.1Mat
Targeted Allele Detail
Nomenclature
Symbol: Ccdc88atm4.1Mat
Name: coiled coil domain containing 88A; targeted mutation 4.1, Masahide Takahashi
MGI ID: MGI:5449207
Gene: Ccdc88a  Location: Chr11:29373658-29510808 bp, + strand  Genetic Position: Chr11, 16.61 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190129
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and FRT flanked pgk-neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:190129)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccdc88a Mutation:  2 strains or lines available
References
Original:  J:190129 Asai M, et al., Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage. Biochem Biophys Res Commun. 2012 Oct 5;426(4):533-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory