Hspb2^tm1.1Ijb
Targeted Allele Detail

Summary

• Symbol: Hspb2^tm1.1Ijb
• Name: heat shock protein 2; targeted mutation 1.1, Ivor J Benjamin
• MGI ID: MGI:5447475
• Gene: Hspb2 Location: Chr9:50662378-50663654 bp, - strand Genetic Position: Chr9, 27.75 cM
• Alliance: Hspb2^tm1.1Ijb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189659
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:189659)

Generation of the Hspb2^tm1.1Ijb allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hspb2 Mutation: 9 strains or lines available

References

• Original: J:189659 Ishiwata T, et al., HSPB2 is dispensable for the cardiac hypertrophic response but reduces mitochondrial energetics following pressure overload in mice. PLoS One. 2012;7(8):e42118
• All: 1 reference(s)