Gt(ROSA)26Sortm1(Pyy)Paba
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(Pyy)Paba |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Paul A Baldock |
MGI ID: |
MGI:5447471 |
Synonyms: |
PYYlox |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(Pyy)Paba page
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Lower bone mass and reduced bone size in Gt(ROSA)26Sortm1(Pyy)Paba/Gt(ROSA)26Sortm1(cre/ERT2)Tyj females
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:189512
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(Pyy)Paba expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Pyy (MGI:99924) |
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Mutation details: A construct containing a CMV promoter, a floxed lacZ and neo cassette and a Pyy gene. Cre mediated recombination results in overexpression of PYY.
(J:189512)
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Schematic diagram of the Gt(ROSA)26Sortm1(Pyy)Paba transgene construct |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
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Original: |
J:189512 Wong IP, et al., Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS One. 2012;7(7):e40038 |
All: |
1 reference(s) |
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