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Tg(Plp)72Kan
Transgene Detail
Nomenclature
Symbol: Tg(Plp)72Kan
Name: transgene insertion 72, Klaus-Armin Nave
MGI ID: MGI:5447029
Synonyms: PLP-tg, PLP-tg72
Transgene: Tg(Plp)72Kan  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Plp)72Kan expresses 1 gene
 
Mutation detailsThe complete transcription unit of the mouse Plp gene, including 3.5 kb of 5' regulatory sequence was used to create this transgenic mouse. Lines 66 and 72 were generated (7 and 3 copies of the transgene respectively). (J:17373)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:17373 Readhead C, et al., Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage. Neuron. 1994 Mar;12(3):583-95
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory