Yap1tm1.1Eno
Targeted Allele Detail
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Symbol: |
Yap1tm1.1Eno |
Name: |
yes-associated protein 1; targeted mutation 1.1, Eric N Olson |
MGI ID: |
MGI:5446483 |
Synonyms: |
Yapfl |
Gene: |
Yap1 Location: Chr9:7932000-8004597 bp, - strand Genetic Position: Chr9, 2.46 cM
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Alliance: |
Yap1tm1.1Eno page
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Lethal cardiomyopathy in Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice
Show the 5 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:189577
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: One loxP site was inserted in intron 2 while an FRT flanked PGK-neo selection cassette followed by a second loxP site was inserted in intron 3. Subsequent excision of the selection cassette left exon 3 flanked by loxP sites.
(J:189577)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Yap1 Mutation: |
37 strains or lines available
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Original: |
J:189577 Xin M, et al., Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal. 2011;4(196):ra70 |
All: |
91 reference(s) |
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