Cd300a^tm1Shib
Targeted Allele Detail

Summary

• Symbol: Cd300a^tm1Shib
• Name: CD300A molecule; targeted mutation 1, Akira Shibuya
• MGI ID: MGI:5445723
• Gene: Cd300a Location: Chr11:114780006-114792772 bp, + strand Genetic Position: Chr11, 80.54 cM
• Alliance: Cd300a^tm1Shib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189144
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neo cassette replaced the coding sequence in exons 1 through 6. Western blot analysis confirmed the absence of protein expression in bone marrow cells. (J:189144)

Generation of the Cd300a^tm1Shib allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd300a Mutation: 21 strains or lines available

References

• Original: J:189144 Nakahashi-Oda C, et al., Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med. 2012 Jul 30;209(8):1493-503
• All: 3 reference(s)