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Targeted Allele Detail
Symbol: Rev3ltm1.1Diaz
Name: REV3 like, DNA directed polymerase zeta catalytic subunit; targeted mutation 1.1, Marilyn Diaz
MGI ID: MGI:5442606
Synonyms: Rev3F
Gene: Rev3l  Location: Chr10:39732118-39875211 bp, + strand  Genetic Position: Chr10, 21.04 cM
Germline Transmission:  Earliest citation of germline transmission: J:188723
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 26. A floxed neo cassette was inserted downstream of exon 25. Cre-mediated recombination removed the neo cassette and left exon 26 floxed. (J:188723)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rev3l Mutation:  73 strains or lines available
Original:  J:188723 Daly J, et al., Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase zeta activity. J Immunol. 2012 Jun 1;188(11):5528-37
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory