Foxg1^tm1.1Fsh
Targeted Allele Detail

Summary

• Symbol: Foxg1^tm1.1Fsh
• Name: forkhead box G1; targeted mutation 1.1, Gordon Fishell
• MGI ID: MGI:5441367
• Synonyms: Foxg1^C:Flpe, FoxG1-C:Flpe, Foxg1^fl
• Gene: Foxg1 Location: Chr12:49429666-49433650 bp, + strand Genetic Position: Chr12, 21.78 cM
• Alliance: Foxg1^tm1.1Fsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188355
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank the Foxg1 coding sequence. In addition, a Flpe gene was inserted 3' of the downstream loxP site, into the 3'end of the endogenous gene. An adjacent frt-flanked neomycin selection cassette was removed via Flp-mediated recombination. Upon cre-mediated recombination, Flpe is expressed from this locus. (J:188355)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxg1 Mutation: 30 strains or lines available

References

• Original: J:188355 Miyoshi G, et al., Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron. 2012 Jun 21;74(6):1045-58
• All: 8 reference(s)