Akr1a1^tm1Maka
Targeted Allele Detail

Summary

• Symbol: Akr1a1^tm1Maka
• Name: aldo-keto reductase family 1, member A1; targeted mutation 1, Masato Kasuga
• MGI ID: MGI:5439954
• Synonyms: AKR1A^-
• Gene: Akr1a1 Location: Chr4:116493707-116508871 bp, - strand Genetic Position: Chr4, 53.26 cM, cytoband C7
• Alliance: Akr1a1^tm1Maka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188043
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: No details provided. Western blot analysis confirmed the absence of protein expression in the liver, kidney and mouse embryonic fibroblasts. (J:188043)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akr1a1 Mutation: 30 strains or lines available

References

• Original: J:188043 Takahashi M, et al., In vivo role of aldehyde reductase. Biochim Biophys Acta. 2012 Nov;1820(11):1787-96
• All: 5 reference(s)