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Tg(Wnt11-TagRFP/cre/ERT2)28Amc
Transgene Detail
Nomenclature
Symbol: Tg(Wnt11-TagRFP/cre/ERT2)28Amc
Name: transgene insertion 28, Andrew P McMahon
MGI ID: MGI:5435691
Synonyms: Wnt11-myrTagRFP-IRES-CE
Transgene: Tg(Wnt11-TagRFP/cre/ERT2)28Amc  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA targeting construct containing a myristoylated Tag-RFPT variant of Red Fluorescent Protein, cre/ERT2 and FRT site flanked Kanamycin/neomycin selection cassette was inserted into the consensus start ATG codon of the mouse Wnt11 gene in the RP23-122D14 BAC. The PGK-Neo/Kan cassette was removed by transient Flpe-recombinase expression. The resulting modified Wnt11-myrTagRFP-IRES-CE BAC transgene was microinjected into (C57BL/6 x DBA) F1 donor eggs. Founder line 28 was subsequently established. (J:159099, J:187213)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wnt11     Summary of all recombinase alleles driven by Wnt11. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:187213 McMahon AP, Generation of a Wnt11-TagRFP/cre/ERT2 transgene. MGI Direct Data Submission. 2012;
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory