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Tmem100tm1.1Ysai
Targeted Allele Detail
Nomenclature
Symbol: Tmem100tm1.1Ysai
Name: transmembrane protein 100; targeted mutation 1.1, Yoshihiko Saito
MGI ID: MGI:5432904
Synonyms: Tmem100-lacZ
Gene: Tmem100  Location: Chr11:90030348-90036508 bp, + strand  Genetic Position: Chr11, 54.75 cM
Abnormal cardiac morphology, pericardial effusion, and growth retardation in Tmem100tm1.1Ysai and Acvrl1tm1Dgen homozygotes

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186473
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Tmem100tm1.1Ysai allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem100 Mutation:  2 strains or lines available
References
Original:  J:186473 Somekawa S, et al., Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12064-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory