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Terttm3Rdp
Targeted Allele Detail
Nomenclature
Symbol: Terttm3Rdp
Name: telomerase reverse transcriptase; targeted mutation 3, Ronald DePinho
MGI ID: MGI:5431942
Synonyms: LSL-mTert
Gene: Tert  Location: Chr13:73627001-73649041 bp, + strand  Genetic Position: Chr13, 40.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186105
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Floxed/Frt)
Mutation:    Insertion
    A floxed neo stop cassette was inserted into intron 1 via homologous recombination. (J:186105)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tert Mutation:  6 strains or lines available
References
Original:  J:186105 Ding Z, et al., Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 2012 Mar 2;148(5):896-907
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory