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Ifngtm3.1Lky
Targeted Allele Detail
Nomenclature
Symbol: Ifngtm3.1Lky
Name: interferon gamma; targeted mutation 3.1, Richard M Locksley
MGI ID: MGI:5317415
Synonyms: GREAT, Ifngtm3(EYFP)Lky
Gene: Ifng  Location: Chr10:118276951-118281797 bp, + strand  Genetic Position: Chr10, 66.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147784
Parent Cell Line:  PC3 (ES Cell)
Strain of Origin:  129S4/SvJae-Tg(Prm-cre)70Og
Mutation
description
Allele Type:    Targeted (No functional change, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed with a loxP-flanked neomycin resistance cassette, an internal ribosome entry site (IRES), and an enhanced yellow fluorescent protein (eYFP) sequence. This vector was inserted downstream of the endogenous translational stop codon and upstream of the 3' untranslated region (UTR). Cre-mediated recombination removed the neo cassette. (J:147784)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ifng Mutation:  41 strains or lines available
References
Original:  J:147784 Reinhardt RL, et al., Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol. 2009 Apr;10(4):385-93
All:  51 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory