Tg(Prnp-AR*112Q)#Deme
Transgene Detail

Summary

• Symbol: Tg(Prnp-AR*112Q)#Deme
• Name: transgene insertion, Diane E Merry
• MGI ID: MGI:5308126
• Synonyms: 112Q
• Transgene: Tg(Prnp-AR*112Q)#Deme Location: unknown
• Alliance: Tg(Prnp-AR*112Q)#Deme page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prnp-AR*112Q)#Deme expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  AR (367)

  Ar	(MGI:88064)

• Mutation details: This transgene consists of the human full-length, expanded androgen receptor containing 112 CAG repeats (112Q) under the control of the prion protein promoter. Two lines were made and the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:134789)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:134789 Chevalier-Larsen ES, et al., Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy. J Neurosci. 2004 May 19;24(20):4778-86
• All: 4 reference(s)