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Esco2tm1.2Ge
Targeted Allele Detail
Nomenclature
Symbol: Esco2tm1.2Ge
Name: establishment of sister chromatid cohesion N-acetyltransferase 2; targeted mutation 1.2, Gregor Eichele
MGI ID: MGI:5308063
Gene: Esco2  Location: Chr14:65819027-65833969 bp, - strand  Genetic Position: Chr14, 34.36 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180371
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination of Esco2tm1.1Ge removed exons 2 and 3. (J:180371)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esco2 Mutation:  10 strains or lines available
References
Original:  J:180371 Whelan G, et al., Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin. EMBO J. 2012 Jan 4;31(1):71-82
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory