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Is(14)5Rdf
Targeted Allele Detail
Nomenclature
Symbol: Is(14)5Rdf
Name: insertion, Chr 14, Riccardo Dalla-Favera 5
MGI ID: MGI:5304347
Gene: Is(14)5Rdf  Location: unknown  Genetic Position: Chr14, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:179879
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsThe targeting vector contained a PGK-Hygro cassette, loxP and FRT sites, inserted in the telomeric region of 14qC3, approximately 2 kb centromeric to the last exon of Rnaseh2b gene.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Is(14)5Rdf Mutation:  1 strain or line available
Notes
This allele was originally generated in cis with Is(14)1Rdf.
References
Original:  J:179879 Lia M, et al., Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines. Blood. 2012 Mar 29;119(13):2981-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory