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Kitltm2.1Sjm
Targeted Allele Detail
Nomenclature
Symbol: Kitltm2.1Sjm
Name: kit ligand; targeted mutation 2.1, Sean J Morrison
MGI ID: MGI:5300820
Synonyms: Scffl
Gene: Kitl  Location: Chr10:100015635-100100416 bp, + strand  Genetic Position: Chr10, 51.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180431
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neo cassette with loxP site was inserted downstream of exon 1 and an additional loxP site was inserted upstream of exon 1. The neo cassette was removed by flp-mediated recombination. (J:180431)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kitl Mutation:  29 strains or lines available
References
Original:  J:180431 Ding L, et al., Endothelial and perivascular cells maintain haematopoietic stem cells. Nature. 2012 Jan 26;481(7382):457-62
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory