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Mapttm1(Setdb1)Akba
Targeted Allele Detail
Nomenclature
Symbol: Mapttm1(Setdb1)Akba
Name: microtubule-associated protein tau; targeted mutation 1, Schahram Akbarian
MGI ID: MGI:5298877
Synonyms: tauSetdb1
Gene: Mapt  Location: Chr11:104231390-104332090 bp, + strand  Genetic Position: Chr11, 67.79 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178512
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapt Mutation:  411 strains or lines available
References
Original:  J:178512 Jiang Y, et al., Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice. Neuropharmacology. 2011 Jun;60(7-8):1088-97
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory