Taar1^tm1Mmil
Targeted Allele Detail

Summary

• Symbol: Taar1^tm1Mmil
• Name: trace amine-associated receptor 1; targeted mutation 1, Mark J Millan
• MGI ID: MGI:5297915
• Gene: Taar1 Location: Chr10:23796304-23797302 bp, + strand Genetic Position: Chr10, 11.39 cM, cytoband A3
• Alliance: Taar1^tm1Mmil page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178061
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of the coding sequence was replaced by an IRES lacZ gene and a floxed neo cassette. Western blot analysis confirmed the absence of transcript expression. (J:178061)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taar1 Mutation: 32 strains or lines available

References

• Original: J:178061 Di Cara B, et al., Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA). J Neurosci. 2011 Nov 23;31(47):16928-16940
• All: 4 reference(s)