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Vsig1tm1Imad
Targeted Allele Detail
Nomenclature
Symbol: Vsig1tm1Imad
Name: V-set and immunoglobulin domain containing 1; targeted mutation 1, Ibrahim M Adham
MGI ID: MGI:5297726
Gene: Vsig1  Location: ChrX:140907608-140939472 bp, + strand  Genetic Position: ChrX, 61.62 cM, cytoband F1
Mutation
origin
Mouse Generated:  Earliest citation of chimera generation: J:178119
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1a was replaced with a neo cassette. (J:178119)
Generatio of the Vsig1tm1Imad allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vsig1 Mutation:  7 strains or lines available
Notes
Very low chimerism is seen and surviving mice fail to produce germ line transmission of this allele.
References
Original:  J:178119 Oidovsambuu O, et al., Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia. PLoS One. 2011;6(10):e25908
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory