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Pdcd10tm1Arte
Targeted Allele Detail
Summary
Symbol: Pdcd10tm1Arte
Name: programmed cell death 10; targeted mutation 1, TaconicArtemis
MGI ID: MGI:5297592
Synonyms: Ccm3fl
Gene: Pdcd10  Location: Chr3:75423797-75464159 bp, - strand  Genetic Position: Chr3, 33.76 cM, cytoband E3
Alliance: Pdcd10tm1Arte page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177584
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Two P-lox sequences were inserted that flank exons 4 and 5 of the murine Pdcd10 gene. (J:229615)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdcd10 Mutation:  18 strains or lines available
References
Original:  J:177584 Boulday G, et al., Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice. J Exp Med. 2011 Aug 29;208(9):1835-47
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory