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Foxj1b2b774Clo
Chemically induced Allele Detail
Nomenclature
Symbol: Foxj1b2b774Clo
Name: forkhead box J1; Bench to Bassinet Program (B2B/CVDC), mutation 774 Cecilia Lo
MGI ID: MGI:5297425
Synonyms: Foxj1T425A, Tails
Gene: Foxj1  Location: Chr11:116330704-116335399 bp, - strand  Genetic Position: Chr11, 81.16 cM
Situs inversus totalis indicated by dextrocardia and dextrogastria

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: B2B/CvDC
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
    This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. (J:175213)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxj1 Mutation:  3 strains or lines available
Notes
Summative Diagnosis:
Laterality defects: Situs inversus totalis and heterotaxy

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
0100 Situs inversus totalis
3608 Left ventricular hypertrophy
3609 Right ventricular hypertrophy
3974 {I,L,I}

References
Original:  J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program. MGI Direct Data Submission (B2B/CvDC). 2011-13;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory