Fcna^tm1Tefu
Targeted Allele Detail

Summary

• Symbol: Fcna^tm1Tefu
• Name: ficolin A; targeted mutation 1, Teizo Fujita
• MGI ID: MGI:5297089
• Gene: Fcna Location: Chr2:25514678-25518042 bp, - strand Genetic Position: Chr2, 17.58 cM, cytoband A3
• Alliance: Fcna^tm1Tefu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177350
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• The promoter and exons 1-3 were replaced with a neomycin resistance cassette. (J:190858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fcna Mutation: 20 strains or lines available

References

• Original: J:177350 Banda NK, et al., Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement. Mol Immunol. 2011 Oct;49(1-2):281-9
• All: 10 reference(s)