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Tg(KRT5-SRC)CJdg
Transgene Detail
Nomenclature
Symbol: Tg(KRT5-SRC)CJdg
Name: transgene insertion C, John DiGiovanni
MGI ID: MGI:5296885
Synonyms: BK5.srcwt
Transgene: Tg(KRT5-SRC)CJdg  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(KRT5-SRC)CJdg expresses 1 gene
 
Mutation detailsThe bovine promoter drives expression of the wild-type human cDNA preceded by a rabbit beta-globin intron and followed by an SV40 polyadenylation sequence in the epidermal basal cells. Several founders were generated with only founder C surviving to produce a line. (J:85132)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:85132 Matsumoto T, et al., Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis. Cancer Res. 2003 Aug 15;63(16):4819-28
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory