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Mcm10tm1Hlee
Targeted Allele Detail
Nomenclature
Symbol: Mcm10tm1Hlee
Name: minichromosome maintenance 10 replication initiation factor; targeted mutation 1, Ho Lee
MGI ID: MGI:5296322
Gene: Mcm10  Location: Chr2:4989714-5012791 bp, - strand  Genetic Position: Chr2, 3.12 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177618
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exons 4 through 6 were replaced with a puro cassette. (J:177618)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mcm10 Mutation:  37 strains or lines available
References
Original:  J:177618 Lim HJ, et al., Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality. Biochim Biophys Acta. 2011 Oct;1813(10):1777-83
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory