Sox9^tm4.1Tlu
Targeted Allele Detail

Summary

• Symbol: Sox9^tm4.1Tlu
• Name: SRY (sex determining region Y)-box 9; targeted mutation 4.1, Thomas Lufkin
• MGI ID: MGI:5293339
• Synonyms: Sox9^flox, Sox9^tm4.Tlu
• Gene: Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
• Alliance: Sox9^tm4.1Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176950
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Flp-mediated recombination removed the neo cassette and left exon 1 floxed. (J:176950)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox9 Mutation: 32 strains or lines available

References

• Original: J:176950 Yap SP, et al., Generation of mice with a novel conditional null allele of the Sox9 gene. Biotechnol Lett. 2011 Aug;33(8):1551-8
• All: 1 reference(s)