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Tg(Avil-cre)1Phep
Transgene Detail
Nomenclature
Symbol: Tg(Avil-cre)1Phep
Name: transgene insertion 1, Paul A Heppenstall
MGI ID: MGI:5292346
Synonyms: Advillin-Cretg
Transgene: Tg(Avil-cre)1Phep  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsRedET recombineering was utilized to insert a cassette containing cre with a nuclear localization signal (NLS), a V5 epitope tag and the SV40 polyadenylation site, into a BAC clone (RP23-109K12) containing the advillin (Avil) locus. Correctly targeted clones were purified and injected into pronuclei of B6D2F1/N oocytes or prepared for intracytoplasmic sperm injection (ICSI). Both methods produced transgenic offspring. The line used for detailed analysis had 5 copies of the cre transgene. (J:176114)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Avil     Summary of all recombinase alleles driven by Avil. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:176114 Zurborg S, et al., Generation and characterization of an Advillin-Cre driver mouse line. Mol Pain. 2011;7:66
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory