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Allele Symbol Allele Name Allele ID |
Tg(Avil-cre)1Phep transgene insertion 1, Paul A Heppenstall MGI:5292346 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
 N |
• no change in pain-related behaviors at 7 days post sciatic nerve injury unlike in global null male mice
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N |
• unlike in global null mice, no change in cytokine profile is seen
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice have normal gross motor and sensory function, assessed with the SHIRPA test
• mice show have comparable acute thrermal nociceptive thresholds (mean reaction times) to controls in hotplate assays
• sensitivity to mechanical nociceptive stimuli (mean paw withdrawal latency, mean force for withdrawal response) is not different from controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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