Adam17^tm1Rain
Targeted Allele Detail

Summary

• Symbol: Adam17^tm1Rain
• Name: a disintegrin and metallopeptidase domain 17; targeted mutation 1, Elaine Raines
• MGI ID: MGI:5284875
• Synonyms: Adam17^deltaEx5
• Gene: Adam17 Location: Chr12:21373510-21423633 bp, - strand Genetic Position: Chr12, 8.3 cM
• Alliance: Adam17^tm1Rain page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174865
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 5 was deleted. (J:174865)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adam17 Mutation: 62 strains or lines available

References

• Original: J:174865 Tang J, et al., Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. Blood. 2011 Jul 21;118(3):786-94
• All: 4 reference(s)